Collagen peptides

nutrient sensing

Sold as a consumer product in 1 of 9 markets tracked.

1 trial had no control group; it improved its main endpoint. 1 trial reported no pre-planned main endpoint. 1 other trial gave a different intervention (Recombinant chimeric type I/type III…) and is shown for context, not counted.

In people: 2 trials (140 people, 12-26 weeks). Doses studied: 15 g/day; 8400 mg.

Evidence map

each mark is a study; size shows participants; hover, tap or focus for details

main endpoints improvedno effectworsenedmixedobservationalanother intervention, contextsize not reported

Higher rows are closer to a person taking this. A case that rests only on the lower rows rests on animals or cells.

What each study measured

outlined square: the main (primary) endpoint

Harms reported

human studies

Where it is available

by regulator; select a market for its source

If you are tracking this yourself

measures the human studies used, by how repeatable they are

Repeatability is whether the same person measured twice gets the same number. It is not statistical significance. It informs study or protocol design only, never advice for a person.

What would change this picture

each study's own statement

Trials under way

Every study (7)

T7 Park 2023 Low-Molecular Collagen Peptide Supplementation and Body Fat Mass in Adults Aged ≥ 50 Years: A Randomized, Double-Blind, Placebo-Controlled Trial doi:10.7762/cnr.2023.12.4.245
T7 Chen 2025 Recombinant type I & III chimeric collagen significantly enhances the vitality of fibroblasts and decelerates the skin aging process doi:10.1186/s12896-025-01050-9
T6 Dakhovnik 2025 A collagen amino acid composition supplementation reduces biological age in humans and increases health and lifespan in vivo doi:10.1038/s41514-025-00280-7
T3 Song 2017 Effect of Orally Administered Collagen Peptides from Bovine Bone on Skin Aging in Chronologically Aged Mice doi:10.3390/nu9111209
T3 Cao 2022 Oral Intake of Chicken Bone Collagen Peptides Anti-Skin Aging in Mice by Regulating Collagen Degradation and Synthesis, Inhibiting Inflammation and Activating Lysosomes doi:10.3390/nu14081622
T3 Mi 2026 Sea Cucumber Collagen Peptides Exert an Anti-Skin Aging Effect by Inhibiting Endoplasmic Reticulum Stress in Fibroblasts doi:10.3390/foods15071147
TX Gunawan 2023 The Effectiveness of Oral Fish Collagen Supplementation on Skin Aging: A Systematic Review and Meta-analysis of Skin Hydration, Skin Elasticity, and Skin Wrinkles doi:10.28933/ajodrr-2023-01-0505ig