Mediterranean dietary pattern

inflammation redoxmetabolic glycemic

Not a regulated product. No approval pathway exists for this intervention in any market, and none is required to practise it.

3 randomized trials (503 people, 13 weeks-6 years). All 3 improved their main endpoint, a measure of physical or cognitive function.

Doses studied: 1 L/week.

Evidence map

each mark is a study; size shows participants; hover, tap or focus for details

main endpoints improvedno effectworsenedmixedobservationalanother intervention, contextsize not reported

Higher rows are closer to a person taking this. A case that rests only on the lower rows rests on animals or cells.

What each study measured

outlined square: the main (primary) endpoint

Harms reported

human studies

Where it is available

by regulator; select a market for its source

If you are tracking this yourself

measures the human studies used, by how repeatable they are

Repeatability is whether the same person measured twice gets the same number. It is not statistical significance. It informs study or protocol design only, never advice for a person.

What would change this picture

each study's own statement

Trials under way

Every study (15)

T7 Martínez-Lapiscina 2013 Virgin olive oil supplementation and long-term cognition: the Predimed-Navarra randomized, trial doi:10.1007/s12603-013-0027-6
T7 Murillo-Zaldívar 2026 Effect of a multicomponent intervention on adherence to the Mediterranean diet in older adults: a randomized controlled trial doi:10.3389/fnut.2026.1918299
T7 Ward 2026 Effect of a PROtein-enriched MEDiterranean diet and EXercise (PROMED-EX) on nutritional status and cognitive performance in older adults at risk of undernutrition and cognitive decline: the PROMED-EX randomized controlled trial doi:10.1016/j.ajcnut.2026.101383
T5 Lagiou 2006 Mediterranean dietary pattern and mortality among young women: a cohort study in Sweden doi:10.1079/BJN20061824
T5 Foscolou 2018 Decomposition of Mediterranean Dietary Pattern on Successful Aging, Among Older Adults: A Combined Analysis of Two Epidemiological Studies doi:10.1177/0898264318780608
T5 Craighead 2005 Mediterranean Diet, Lifestyle Factors, and Mortality doi:10.1001/jama.293.6.674-a
T5 Bulló 2011 Bone quantitative ultrasound measurements in relation to the metabolic syndrome and type 2 diabetes mellitus in a cohort of elderly subjects at high risk of cardiovascular disease from the predimed study doi:10.1007/s12603-011-0046-0
TX Tang 2021 Mediterranean Diet and Mortality in People with Cardiovascular Disease: A Meta-Analysis of Prospective Cohort Studies doi:10.3390/nu13082623
TX Mediterranean Diet, Lifestyle Factors, and… (2005) Mediterranean Diet, Lifestyle Factors, and Mortality doi:10.1001/jama.293.6.674-b
TX Aiello 2020 Effects of nutraceuticals of Mediterranean diet on aging and longevity doi:10.1016/B978-0-12-818649-7.00047-3
TX Zamroziewicz 2018 The Mediterranean Diet and Healthy Brain Aging: Innovations From Nutritional Cognitive Neuroscience doi:10.1016/B978-0-12-811959-4.00002-X
TX Pederiva 2026 Editorial: Multidimensional benefits of the Mediterranean diet across the lifespan and cultures doi:10.3389/fnut.2026.1854446
TX Buckland 2015 The Mediterranean Diet and Mortality doi:10.1016/b978-0-12-407849-9.00005-1
TX Pandey 2018 Mediterranean Diet and Its Impact on Cognitive Functions in Aging doi:10.1016/B978-0-12-811959-4.00010-9
TX Abrahim 2021 No-added-oil mediterranean diet: A novel aging deceleration diet? doi:10.1016/j.ahr.2021.100017