Overview / Research screener / Resveratrol
OTC Nutraceuticals
Resveratrol (sirtuin activator, STAC)
nutrient sensing
Sold as a consumer product in 1 of 9 markets tracked; in clinical trials in 3.
Evidence so far is from animal studies.
Evidence map
main endpoints improvedno effectworsenedmixedobservationalanother intervention, contextsize not reported
Higher rows are closer to a person taking this. A case that rests only on the lower rows rests on animals or cells.
What each study measured
Harms reported
Where it is available
If you are tracking this yourself
Repeatability is whether the same person measured twice gets the same number. It is not statistical significance. It informs study or protocol design only, never advice for a person.
What would change this picture
Trials under way
Every study (13)
- T3 Gerhardt 2011 Idebenone and Resveratrol Extend Lifespan and Improve Motor Function of HtrA2 Knockout Mice doi:10.1371/journal.pone.0028855
- T3 Oomen 2009 Resveratrol preserves cerebrovascular density and cognitive function in aging mice doi:10.3389/neuro.24.004.2009
- T3 Okamoto 2022 Short-term resveratrol treatment restored the quality of oocytes in aging mice doi:10.18632/aging.204157
- TX Bhullar 2015 Lifespan and healthspan extension by resveratrol doi:10.1016/j.bbadis.2015.01.012
- TX Liu 2012 Activation of SIRT1 by Resveratrol requires lamin A doi:10.18632/aging.100532
- TX Sarubbo 2020 Resveratrol, SIRT1, oxidative stress, and brain aging doi:10.1016/B978-0-12-818698-5.00033-X
- TX Timmers 2012 The journey of resveratrol from yeast to human doi:10.18632/aging.100445
- TX Blagosklonny 2009 Inhibition of S6K by resveratrol: In search of the purpose doi:10.18632/aging.100059
- TX Toniolo 2020 Resveratrol, aging, and fatigue doi:10.1016/B978-0-12-818698-5.00032-8
- TX Rouse 2018 Resveratrol in Aging and Age-Related Diseases doi:10.1016/B978-0-12-811353-0.00079-8
- TX Hemmati 2020 Quercetin and resveratrol, aging and kidney doi:10.1016/B978-0-12-818698-5.00030-4
- TX Chung 2012 Using PDE inhibitors to harness the benefits of calorie restriction: lessons from resveratrol doi:10.18632/aging.100442
- TX Arbor 2018 Where and How in the mTOR Pathway Inhibitors Fight Aging: Rapamycin, Resveratrol, and Metformin doi:10.5772/intechopen.79338