Market atlas / Senolytics / Quercetin

Quercetin (senolytic flavonoid)

traditional-to-validatedsmall-moleculesenolyticflavonoid● senescent-cell-burden

Stage by geography

signalpreclinfirst-in-humanRCTapprovedreal-worldconsumerUSCN

MarketsUS United States FDAUK United Kingdom MHRA / NICECN China NMPAIN India CDSCOJP Japan PMDACH Switzerland SwissmedicSG Singapore HSAIL Israel Ministry of HealthKR South Korea MFDS

What each market approved it for

Market	Stage	Since	Indication / class / form
US	consumer	not dated	not published
CN	RCT	2023-02-05	not published

Biomarker trends

no biomarker readings yet

Studies

The studies on Quercetin, what they found, in whom and how strongly, are on its evidence page, each linked to its source.

What the trials measure

Registered primary outcomes this development's trials are powered on, commonest first (ClinicalTrials.gov). What is measured, across markets.

Registered primary endpoint	Markets measuring it
Senescent cell abundance in blood (p16INK4A)	US
Urinary Lactulose Excretion	US
Plasma Quercetin	US
Change in Walking Speed	US
Blood Pressure	US
Weight	US
Heart Rate	US
Plasma TNF-a	US
Plasma Il-6	US
HSP70 content of peripheral blood mononuclear cells	US

Connections

Trajectory

2010

MarketUS: rct (clinical trials (highest phase 2))

NCT00065676 · machine-extracted

2016

Relatedshares a mechanism with Dasatinib

NCT02848131 · machine-extracted

2016

ProfileQuercetin (senolytic flavonoid)

NCT02848131 · machine-extracted

2023

MarketCN: rct (clinical trials (highest phase 2))

NCT05724329 · machine-extracted

2026

MarketUS: consumer (US dietary supplement (DSHEA), not FDA-approved as a drug)

DSLD:320266 · machine-extracted

Get into the weeds: raw observations + provenance

quer_us_trial  2026-06-29  kind=geography_stage  verify=M
   Quercetin: US phase 2 trials [NCT00065676]
   source NCT00065676  https://clinicaltrials.gov/study/NCT00065676

quer_edge_dasa  2026-06-29  kind=edge  verify=M
   the D+Q senolytic pair
   source NCT02848131  https://clinicaltrials.gov/study/NCT02848131

quer_facets  2026-06-29  kind=facets  verify=M
   Quercetin facets
   source NCT02848131  https://clinicaltrials.gov/study/NCT02848131

quer_cn  2026-06-29  kind=geography_stage  verify=M
   Quercetin: a registered phase 2 trial in China [NCT05724329]
   source NCT05724329  https://clinicaltrials.gov/study/NCT05724329

quer_us_consumer  2026-06-29  kind=geography_stage  verify=M
   Quercetin sold as a US dietary supplement
   source DSLD:320266  https://dsld.od.nih.gov/label/320266