Market atlas / Other / Vitamin D
Vitamin D (D3, cholecalciferol)
traditional-to-validatedsupplementvitamin-d-receptorcalcium-bone-metabolism● 25-hydroxyvitamin-d
Stage by geography
signalpreclinfirst-in-humanRCTapprovedreal-worldconsumerUSUKCNJPILSG+3 stages
MarketsUS United States FDAUK United Kingdom MHRA / NICECN China NMPAIN India CDSCOJP Japan PMDACH Switzerland SwissmedicSG Singapore HSAIL Israel Ministry of HealthKR South Korea MFDS
What each market approved it for
| Market | Stage | Since | Indication / class / form |
|---|---|---|---|
| US | consumer | not dated | not published |
| UK | signal | not dated | not published |
| CN | signal | not dated | not published |
| JP | signal | not dated | not published |
| SG | RCT | not dated | not published |
| IL | signal | not dated | not published |
Legal status by market
| Market | Legal class | Effective | Status & source |
|---|---|---|---|
| US | Dietary supplement | not dated | Sold as a US dietary supplement; label on file in the NIH Dietary Supplement Label Database (Vitamin World Vitamin D3 2,000 IU). |
Biomarker trends
no biomarker readings yet
Studies
The studies on Vitamin D, what they found, in whom and how strongly, are on its evidence page, each linked to its source.
What the trials measure
Registered primary outcomes this development's trials are powered on, commonest first (ClinicalTrials.gov). What is measured, across markets.
| Registered primary endpoint | Markets measuring it |
|---|---|
| Cognitive impairment improvement | CN |
| Change in BMD (Z score) following 10 months of vitamin D supplementation | IL |
| Prevalence of pneumonia | JP |
| Rate of symptomatic outcome | SG |
| Change in vitamin D status (25-hydroxyvitamin D serum concentration) | UK |
| Glucose tolerance and insulin sensitivity | US |
| Rate of Absorption of vitamin D3 to blood | US |
| Change in total serum 25D | US |
| The primary outcome is the proportion of postmenopausal women with D inadequacy defined by current consensus as a serum 25(OH)D <… | US |
| Number of Participants With an AMD Event | US |
Connections
no connections yet
Trajectory
2026
Legal statusUS: dietary supplement. Sold as a US dietary supplement; label on file in the NIH Dietary Supplement Label Database (Vitamin World Vitamin D3 2,000 IU).
DSLD:62813 · machine-extracted
Get into the weeds: raw observations + provenance
legal__US__otc_vitamin_d 2026-09-28 kind=legal_status verify=M otc_vitamin_d in US: dietary-supplement (Sold as a US dietary supplement; label on file in the NIH Dietary Supplement Label Database (Vitamin World Vitamin D3 2,000 IU).) source DSLD:62813 https://dsld.od.nih.gov/label/62813 vitamin_d_facets 2026-09-28 kind=facets verify=M Vitamin D (D3, cholecalciferol) facets (mechanism tags pending curator review) source NCT01745263 https://clinicaltrials.gov/study/NCT01745263 vitamin_d_us 2026-09-28 kind=geography_stage verify=M Vitamin D is sold in the US as a dietary supplement (Vitamin World Vitamin D3 2,000 IU) source DSLD:62813 https://dsld.od.nih.gov/label/62813 ctsearch__CN__otc_vitamin_d 2026-09-29 kind=geography_stage verify=M vitamin d: 1 registered trial(s) in CN, highest phase ? [NCT03401619] source NCT03401619 https://clinicaltrials.gov/study/NCT03401619 ctsearch__IL__otc_vitamin_d 2026-09-29 kind=geography_stage verify=M vitamin d: 1 registered trial(s) in IL, highest phase ? [NCT01694355] source NCT01694355 https://clinicaltrials.gov/study/NCT01694355 ctsearch__JP__otc_vitamin_d 2026-09-29 kind=geography_stage verify=M vitamin d: 1 registered trial(s) in JP, highest phase ? [NCT00877422] source NCT00877422 https://clinicaltrials.gov/study/NCT00877422 ctsearch__SG__otc_vitamin_d 2026-09-29 kind=geography_stage verify=M vitamin d: 1 registered trial(s) in SG, highest phase 2 [NCT04267809] source NCT04267809 https://clinicaltrials.gov/study/NCT04267809 ctsearch__UK__otc_vitamin_d 2026-09-29 kind=geography_stage verify=M vitamin d: 1 registered trial(s) in UK, highest phase ? [NCT02495584] source NCT02495584 https://clinicaltrials.gov/study/NCT02495584 ctsearch__US__otc_vitamin_d 2026-09-29 kind=geography_stage verify=M vitamin d: 6 registered trial(s) in US, highest phase ? [NCT01145703] source NCT01145703 https://clinicaltrials.gov/study/NCT01145703