Market atlas / Mitochondrial / Coenzyme Q10

Coenzyme Q10 (mitochondrial cofactor)

traditional-to-validatedsmall-moleculemitochondrial-electron-transportantioxidant● coq10-levels

Stage by geography

signalpreclinfirst-in-humanRCTapprovedreal-worldconsumerUSCNJPSGIL

MarketsUS United States FDAUK United Kingdom MHRA / NICECN China NMPAIN India CDSCOJP Japan PMDACH Switzerland SwissmedicSG Singapore HSAIL Israel Ministry of HealthKR South Korea MFDS

What each market approved it for

Market	Stage	Since	Indication / class / form
US	consumer	not dated	not published
CN	RCT	2015-07-01	not published
JP	RCT	not dated	not published
SG	RCT	not dated	not published
IL	RCT	not dated	not published

Biomarker trends

no biomarker readings yet

Studies

The studies on Coenzyme Q10, what they found, in whom and how strongly, are on its evidence page, each linked to its source.

What the trials measure

Registered primary outcomes this development's trials are powered on, commonest first (ClinicalTrials.gov). What is measured, across markets.

Registered primary endpoint	Markets measuring it
Veterans Short Form 36-Item Health Survey Physical Component Summary	US
Evaluate the efficacy coenzyme Q10 in the treatment of myalgia in patients receiving statin therapy	US
Embryo mitochondrial DNA (mtDNA)	US
Serum coenzyme Q10 levels	US
Efficacy of Coenzyme Q10 (Unified Parkinson's Disease Rating Scale [UPDRS] AND Progressive Supranuclear Palsy Rating Scale…	US
Phosphocreatine Recovery	US
Percentage of Participants With Reduction in Muscle Pain Associated With Statin Use	US
Maximum tolerated dose of CoQ10 that does not alter the pharmacokinetics of doxorubicin	US
PCr recovery measured by 31 phosphorus magnetic resonance spectroscopy	US
Effects of Coenzyme Q10 on Fatigue (as Measured by POMS-F) 24 Weeks Following Randomization	US

Connections

no connections yet

Trajectory

2006

ProfileCoenzyme Q10 (mitochondrial cofactor)

NCT00327756 · machine-extracted

2006

MarketUS: rct (clinical trials (highest phase 2))

NCT00327756 · machine-extracted

2015

MarketCN: rct (clinical trials (highest phase 3))

NCT02407548 · machine-extracted

2026

MarketUS: consumer (US dietary supplement (DSHEA), not FDA-approved as a drug)

DSLD:185215 · machine-extracted

2026

MarketIL: rct (clinical trials (highest phase 3))

NCT02042482 · machine-extracted

2026

MarketJP: rct (clinical trials (highest phase 3))

NCT01126697 · machine-extracted

2026

MarketSG: rct (clinical trials (highest phase 3))

NCT01892176 · machine-extracted

Get into the weeds: raw observations + provenance

coq_facets  2026-06-29  kind=facets  verify=M
   CoQ10 facets
   source NCT00327756  https://clinicaltrials.gov/study/NCT00327756

coq_us_trial  2026-06-29  kind=geography_stage  verify=M
   Coenzyme Q10: US phase 2 trials [NCT00327756]
   source NCT00327756  https://clinicaltrials.gov/study/NCT00327756

coq_cn  2026-06-29  kind=geography_stage  verify=M
   Coenzyme Q10: a registered phase 3 trial in China [NCT02407548]
   source NCT02407548  https://clinicaltrials.gov/study/NCT02407548

coq_us_consumer  2026-06-29  kind=geography_stage  verify=M
   Coenzyme Q10 (ubiquinone / ubiquinol) sold as a US dietary supplement
   source DSLD:185215  https://dsld.od.nih.gov/label/185215

ctsearch__IL__dev_coq10  2026-07-10  kind=geography_stage  verify=M
   coenzyme Q10: 4 registered trial(s) in IL, highest phase 3 [NCT02042482]
   source NCT02042482  https://clinicaltrials.gov/study/NCT02042482

ctsearch__JP__dev_coq10  2026-07-10  kind=geography_stage  verify=M
   coenzyme Q10: 2 registered trial(s) in JP, highest phase 3 [NCT01126697]
   source NCT01126697  https://clinicaltrials.gov/study/NCT01126697

ctsearch__SG__dev_coq10  2026-07-10  kind=geography_stage  verify=M
   coenzyme Q10: 1 registered trial(s) in SG, highest phase 3 [NCT01892176]
   source NCT01892176  https://clinicaltrials.gov/study/NCT01892176